September 2025

Oceanography | Vol. 38, No. 3

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reproduction, photosynthetic efficiency, behavior, predator-prey

interaction, chemical signaling and sensing, epigenetics, and much

more. There have been a number of attempts, using meta-analyses,

to group responses by organism type (Kroeker et al., 2013; Alter

et al., 2024), trophic level, and/or geographic location (Busch and

McElhany, 2016; Hu et al., 2024). These results have been used to

discuss socioeconomic impacts, such as those on fisheries and

aquaculture (Barton et al., 2015; Narita and Rehdanz, 2017) as well

as on human health (Falkenberg et al., 2020).

Some of the varying responses to OA can be accounted for by

experiment duration (short-term experiments having more of an

acute effect than longer-term acclimation experiments; e.g., Form

and Riebesell, 2012) or by the method of acidification used (Hurd

et al., 2009). These inconsistencies led to the development of com-

munity best practice guides (Riebesell et al., 2011) designed to

promote more robust ongoing and future research that would be

repeatable and useful for meta-analysis. It also led to the OA-ICC

providing two online databases: a bibliographic database that can

be shared using Zotero or pCloud, and a database on the impacts

of ocean acidification on marine organisms.

Researchers also need to consider spatial variation in marine

ecosystems: how organisms have acclimated and adapted to their

environments, and what this means for their responses to future

change (e.g., Lewis et al., 2013; Vargas et al., 2022). Short-term,

local fluctuations can result in different responses for marine

organisms that are exposed to them compared to organisms

exposed to less variable environments (e.g., Mangan et al., 2019;

Lowder et al., 2022).

HOW GOAL 2 SUPPORTS mCDR RESEARCH

Understanding ecosystem responses is fundamental for evalu-

ating the ecological implications of mCDR techniques. Research

on OA provides insights into the vulnerabilities of various species

and habitats to changing carbonate chemistry, helping to predict

which life stages, species, or habitats to focus on first in mCDR

impact studies, or helping to generate risk analyses for species

responses (Bednaršek et al., 2025). For example, early life stages

are likely to be most sensitive, and both calcifying and photosyn-

thetic organisms have additional energetic requirements for main-

taining internal physiology against shifting carbonate chemistry

in surrounding seawater. Calcifying and photosynthetic organ-

isms may respond to mCDR conditions, especially at the point

source of the activity, because of their direct reliance on compo-

nents of the carbonate system. Understanding the dynamics of any

discharge plume and its dilution moving away from the source

will be important for determining the exposure, and therefore the

vulnerability, of organisms and ecosystems. Additionally, fluctu-

ating exposure to plumes could result in different responses than

continued exposure.

In the case of seaweed cultivation and nutrient fertilization, it

will be critical to understand how large-scale farming or nutrient

additions or removals might affect a variety of ecosystems, not

just the immediate ecosystem being manipulated. Large-scale cul-

tivation or nutrient addition could alter habitats and biodiversity,

shift nutrient availability (cause nutrient “robbing”), and alter the

deep-sea environment. The GOA-ON community is again useful

here as it is not solely focused on the surface ocean, but members

also study the interior and deep ocean and their ecosystems. Use

of the latest biological mapping methods combined with sensitiv-

ity analysis from the OA community could be transformative in

assessing potential habitat and ecosystem vulnerabilities to dif-

ferent mCDR interventions.

Clarity in the methods used to change the carbonate chemis-

try, as well as how impacts to organisms are measured, is vitally

important to make sure experiments and field studies are com-

parable. A highlight from the OA community has been the prin-

ciple that experiments should be reported clearly and conducted

according to published best practices, allowing results to be col-

lated for data transparency (OA-ICC, 2023) and metadata anal-

yses. The production of a guide to best practices for ocean alka-

linity enhancement (Oschlies et  al., 2023), with input many

GOA-ON members, is a positive step toward creating a coor-

dinated research effort. While there is an understandable need

to focus on key marine organisms for experimental purposes,

understanding the consequences of any ecosystem-scale impacts

is more complex and ties into the need to co-develop modeling

and monitoring processes. Determining these complex inter-

actions exemplifies the need for a community approach to con-

sider impacts from multiple angles using multiple techniques.

Organisms are exposed to multiple stressors, and changes in

carbonate chemistry can act with other variables synergistically,

additively, or antagonistically (Secretariat of the Convention on

Biological Diversity, 2014). For mCDR research, key questions in

preparation for experimentation will be whether to test impacts

individually or in combination with other stressors, which can

be informed by the existing body of OA research, such as that

developed by the SCOR Changing Ocean Biological Systems

working group.

Finally, the biology working group of GOA-ON has devel-

oped a conceptual framework for the biological monitoring

needed to be able to attribute observed changes in the field to OA

(Widdicombe et al., 2023). In addition to the GOA-ON biologi-

cal working group, a number of other groups are looking at estab-

lishing biological indicators for OA (e.g., Bednaršek et al., 2019).

These activities are useful to consider for mCDR, in particular

for identifying potentially vulnerable species, which can then be

mapped to determine where they may be at risk of impact or ben-

efit from mCDR. For instance, for environmental MRV, consid-

ering specific biological indicators that are known to respond to

changes in carbonate chemistry could be useful for monitoring

impact at mCDR field trials (and if mCDR techniques are scaled).